Radeon Ubuntu Linux Users Have A Lot To Gain By Upgrading Mesa
With Metro Last Light Redux on the RX 480 you'll see a 50% performance boost right away by simply moving to Mesa 13.0+, but the performance was unchanged past that point.
Dota 2 with OpenGL didn't budge much, but at least with Mesa 13.0+ there is the option of using the RADV Vulkan driver.
Counter-Strike: Global Offensive actually regressed with Mesa 13.0, but seems to have largely recovered with Mesa Git.
Moving to Mesa 13.0 or 17.0-devel will yield about a 66% performance improvement for the Radeon RX 480 over what's found by default in Ubuntu 16.10.