Originally posted by Sidicas
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The vast majority will run the game at their LCD's native resolution with all settings maxed that they can get away with before looking at what they can do with AA settings. your goal with AA is to reduce jagged edges, if you are lowering the resolution and using lower detail levels on the textures then even with AA turned up it's going to look like crap.
Performance tuning though would be playing with the settings of the usual biggest performance impactors like soft shadows, dynamic lighting and AA settings since AF settings are almost free on GPUs from the last 5-6 years.
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