I've Been Running GNOME Wayland On My Primary Dev System: It's Been Going Great
Simply put, the experience has been going great with using GNOME 3.18 from Fedora 23 on Wayland natively rather than the X.Org Server. For Fedora 23, X11 remains the default, but the stars are still aligning where it looks like for Fedora 24 the GNOME Wayland-powered desktop will be the default.
This development box is basically my secondary system: on my primary system where I write my articles, emails, Internet use, etc, it's still running Fedora 21 until I switch to Fedora 23 when upgrading from a Broadwell to Skylake system. However, on the system next to it is where I do much of my Phoronix Test Suite / Phoromatic / OpenBenchmarking.org development work, etc.
Previously On Phoronix: GNOME 3.18 On Fedora 23: X.Org vs. Wayland Performance
So far I haven't encountered any real issues albeit most of my applications there are limited to the terminal, gedit, gFTP, GIMP, etc. After week one I'm happy with the experience and plan to continue using the Wayland environment there and will also try it out on my main production system once moving to Fedora 23.
If I run into any issues, of course I'll be sure to express it on Phoronix. But overall I'm happy and looking forward to Fedora 24 hopefully being the first tier-one Linux workstation/desktop distribution using it by default next year. I'm also excited about the continuing Wayland improvements coming for GNOME 3.20.