Originally posted by schmidtbag
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HP-UX, the big one, got an abortive x86 port in 2009-2010 that never shipped to customers. NEC also shipped systems running UX (ones that weren't just HP rebadges - Oki, Hitachi, and Mitsubishi Electric rebadged HP's machines for the Japanese market, but NEC did true HP-compatible servers.) Basically all very large HP systems (anything capable of npars, essentially) ran UX, with a few running Windows for the very-large-MSSQL market. Beckton and DL980 made that irrelevant, though, so Microsoft pulled out. UX is still supported until the end of 2025 and a lot of users are in frantic migration mode.
VMS never sold huge volume on IPF and was almost all small systems, but they were very important to the customers who used them, especially industrial control. HP was in the process of euthanizing it when VSI bought the IP and did the x86 port.
Nonstop was low-volume but very profitable, especially in telco and finance (mainly debit.) HP ported it to x86 a while back.
There were also a few third-party systems...
Windows/IPF basically existed for the large MSSQL market, as mentioned, at a time where a credible 16-or-more-sockets x86 system just didn't exist. It was actually fairly successful in its little niche.
Linux/IPF was used most notably for HPC in the US, via SGI's Altix systems, but had some success in the big-box market, especially in Asia. Inspur was designing new Linux/IPF systems well into the 2010s as part of the PRC's "domestic mainframe" initiative. Fujitsu and Hitachi had limited success, mainly in the Japanese market, with Linux/IPF on their scale-up systems as a mission-critical option somewhere in between conventional RISC/UNIX and commodity.
Secure64 had an Itanium-specific microkernel OS for network appliances with some really neat features.
Bull and NEC both had mainframe operating systems (GCOS 7/8 for Bull, ACOS-4 for NEC) running emulated on IPF systems.
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