It has explicit support for Linux in the BIOS.
All the sensor hardware is detected and works great.
The on-board video will only work in SVGA mode, but I disabled it and got a real video card.
It's really a server motherboard, so it has no PCIe x16 slot.
You can use a PCI-e x8 to x16 adapter (from orbitmicro.com) to plug in a PCIe x16 video card with no noticeable loss in performance.
Performance and compatibility are OUTSTANDING. It's only SuperMicro for me from now on.