It's one of the last major distribution updates coming out this year, but Fedora 12
(codenamed "Constantine") is now available. Fedora 12 features performance improvements, Ogg Theora 1.1 support, graphics improvements (including ATI kernel mode-setting by default), many virtualization improvements, PulseAudio improvements, Multi-Pointer X with X.Org 7.5 / X Server 1.7, and many other new features.
The Fedora 12 release announcement can be read on the Fedora Wiki
while the various spins of Fedora 12 can be downloaded at FedoraProject.org