Eduardo Lima Mitev of Igalia has been working ion hardware acceleration for GNOME and for the past few months has been working to bring OpenCL closer to GNOME. The fruit of this work is GOCL, a GLib/GObject library to simplify OpenCL usage in GNOME software. GOCL exposes a simpler API and an interface that is closer to what GNOME developers are used to seeing with GLib, GError, and GObject Introspection.
The GOCL API right now is rather simply and doesn't yet expose an asynchronous API and is missing some other OpenCL bits but there is full GTK-DOC documentation available and all of the code is available on GitHub.
More details can be found in this Igalia blog post.