With the HMMer molecular biology test, the AMD parts returned to being competitive with Intel. The A10-5800K for HMMer was only a slight improvement over the A8-3870K, but still it was faster than the Core i3 CPUs and when overclocked it beat out the i5-2400S.
With the last molecular biology test run for this article, MAFFT, the performance again was right between the tested i3 and i5 CPUs from Intel.
While AMD processors had trouble with some of the earlier scientific tests, when it comes to John The Ripper with the Blowfish performance, they do very well. The A10-5800K at its stock frequencies was right ahead of the Intel Core i5 2500K. When overclocked, the A10-5800K at 4.4GHz outperformed the Ivy Bridge Core i5 3470.