its impossible to hurt your health with GBL source: "↑ NTP Study Reports TR-406 Toxicology and Carcinogenesis Studies of γ-Butyrolactone (CAS No. 96-48-0) in F344/N Rats and B6C3F1 Mice (Gavage Studies) oder Cognitive Enhancement Research Institute Discussion." this source prove you life longer with GBL than without.
its also impossible to kill you with LSD : http://de.wikipedia.org/wiki/LSD#Angaben_zur_Giftigkeit
"that the ratio of effective dose to lethal dose in humans is approximately 1:1000, that is a thousand times the dose of an effective dose in humans would lead to fatal poisoning (for comparison, alcohol and nicotine, this value is approximately 1:8). Pharmacists assume a therapeutic range from 280th This would be a safe drug LSD. " source: ↑ Zitiert aus: Robert M. Julien: Drogen und Psychopharmaka. Spektrum Verlag, 1997. Quelle: Gable, R.S. (1993): Toward a Comparative Overview of Dependence Potential and Acute Toxity of Psychoactive Substances Used Nonmedically. In: American Journal of Drug and Alcohol Abuse. Bd. 19, S. 263–281.
you can overdose LSD 999 times and you will not die. this means its a very save drug in medical use.
also LSD is a proved medicine against alcoholism:
"Studies in the 1950s, noted in the treatment of alcoholism with LSD, a success rate of 50 percent.   The success rate of Alcoholics Anonymous is however only about 10%.  However, some LSD studies due to methodological criticized shortcomings and different groups had different results. In a 1998 article published the works were re-examined on the subject. It was concluded that the question of the efficacy of LSD in treating alcoholism is unanswered so far.  A 2012 meta-analysis confirmed the original published in the studies noted beneficial effect.  "
also its a proved medicine against Cluster headache! "↑ R. Andrew Sewell, John H. Halpern & Harrison G. Pope Jr: Response of cluster headache to psilocybin and LSD. In: Neurology. Bd. 66, 2006, S. 1920–1922, PMID 16801660 (PDF; 239 KB)"
also its a proved medicine against cancer pain: "↑ Peter Gasser: LSD-unterstützte Psychotherapie bei Personen mit Angstsymptomatik in Verbindung mit fortgeschrittenen lebensbedrohenden Erkrankungen"
and all these studies never ever result in a permanent psychotic episode